/ Sperm Content for UC Davis en /blog/dna-organizing-protein-offers-new-insight-infertility-ivf-and-generational-health <p>The causes of male infertility can be hard to diagnose, with many tests failing to detect genetic defects. Sometimes, infertility doesn’t even involve the genes themselves. It can arise from improper folding of the father’s DNA in the sperm. If a couple conceives, this mispackaged DNA can damage the lifelong health of the child.</p> May 19, 2026 - 2:08pm Andy Fell /blog/dna-organizing-protein-offers-new-insight-infertility-ivf-and-generational-health /news/3d-genome-structure-guides-sperm-development How 3D folding of DNA inside germ cells sets them on the path to become sperm. March 03, 2025 - 11:22am Andy Fell /news/3d-genome-structure-guides-sperm-development /blog/protein-integral-sperm-development-and-male-fertility-identified <p><span>Early in the development of sperm, a strange event happens: the X and Y chromosomes condense into tight packages and are sequestered away from the other 44 human chromosomes. If any part of this process goes awry, the cells cannot mature into sperm. Researchers in the UC Davis College of Biological Sciences have now identified an important link in this process — a little-known protein called ATF7IP2.</span></p> February 21, 2024 - 3:20pm Andy Fell /blog/protein-integral-sperm-development-and-male-fertility-identified