Identifying Genetic Causes of Blindness in People and Macaques

Andy Fell — April 28, 2026 - 3:25pm

An inherited form of blindness directly comparable to a common inherited optic nerve disease in humans has been discovered in rhesus macaques at the California National Primate Research Center at the University of California, Davis. The work, published April 15 in Proceedings of the National Academy of Sciences, could lead to a better understanding of autosomal dominant optic atrophy, or ADOA, and potentially to new treatments.

$3.5 Million Grant to Study Disease Causing Vision Loss in Children

Andy Fell — February 23, 2023 - 11:16am

Autosomal dominant optic atrophy (ADOA) is a rare genetic disease that causes progressive and irreversible vision loss in both eyes starting in the first decade of life. There is currently no treatment for ADOA, which affects approximately 3 people per 100,000 worldwide.

UC Davis researchers will use a new 3.5 million grant from the National Eye Institute, part of the National Institutes of Health, to develop a nonhuman primate model of ADOA to speed the development and testing of treatments for humans.

Blindness Content

Identifying Genetic Causes of Blindness in People and Macaques

$3.5 Million Grant to Study Disease Causing Vision Loss in Children